MT 126 - Extractable acids

 

Content Handbook F

 

Outline of method

A solution of the formulation as specified in the appropriate monograph is prepared, and acidified with hydrochloric acid. The precipitated acids are extracted with diethyl ether. The ether is removed by evaporation and the residue is dissolved in neutral ethanol. This solution of the acids is titrated with sodium hydroxide, using the specified indicator.