MT 179 - Dissolution degree and solution stability

 

Content Handbook H

 

Outline of method

The SG formulation is dissolved in Standard water in a graduated 250 ml cylinder at 25 °C. After 15 inversions and a standing time of 5 minutes, the contents are poured over a 75 ìm sieve. The residue on the sieve is quantified. The stability of the solution is checked by allowing the filtrate to stand for a period of 18 hours and filtering it again through a 75 ìm sieve

Scope

The method is intended for the determination of the degree of dissolution and the stability of solution of water soluble granules.